New drugs help resolve nerve pain without addiction - but you may not need them

Volume 6    |    Issue 20

If you suffer from nerve damage, the pain can be horrible. And if you have to be in the cold for very long, the pain is unbearable. But Japanese scientists say they have found a new way to reduce this terrible pain.

Researchers from Hiroshima University identified a specific molecule involved in maintaining pain after a nerve injury. They also found a way to block it.

To make the discovery, the researchers took mice with an injury to their sciatic nerve and gave them multiple injections of a drug that blocks the activity of a molecule called high-mobility group box-1 (HMGB1). After the injections, the mice showed less pain. However, this wasn't the only drug that showed these results. They also found that matrix metalloprotease-9 (MMP-9) could alleviate pain from the injury. MMP-9 is a drug that blocks the activity of a different molecule. But this drug took only one injection to block the pain.

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This is good news because the chemical pathways that these drugs use to inhibit HMGB1 or MMP-9 are different from common pain relievers. Pain relievers like opioids (Morphine) are highly addictive and other painkillers like acetaminophen (Tylenol) have unwanted side effects. The researchers are hopeful that these two new drugs could reduce the potential for addiction or negative side-effects.

While these results reveal a promising therapeutic strategy for treating neuropathic pain without addiction, it's not where you should start if you have nerve pain. I showed you a few weeks ago how to relieve sciatic nerve pain using a simple mineral. If you have sciatic nerve pain on the right side of your back, take some potassium (no more than 99 mg daily). If your sciatica is on the left side, take some sodium (eat some celery or sea salt). Most sciatic pain is on the right side.

If this isn't enough, or if your nerve pain is elsewhere on the body, there are other nutrients that can help heal the damage and reduce the pain. You'll find many of these nutrients, such as phosphorus, acetyl-l-carnitine, and alpha-lipoic acid, in Advanced Nerve Support.

Finally, if your nerve pain is accompanied by sugar cravings, uncontrollable weeping, and the pain seems to disappear when you're walking (but intensifies when sitting), then you could have a magnesium deficiency. You can take up to 1,000 mg daily to alleviate the deficiency.

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