With CoQ10 and Heart Failure, Taking More Is Better

Volume 6    |    Issue 98

Even before statins started causing heart failure, alternative doctors have been telling their heart patients to take CoQ10. The nutrient is vital for heart health. And statins force the liver to stop producing the nutrient. This is why doctors who still prescribe statins will tell their patients to take CoQ10 along with it. But are you taking enough CoQ10 to prevent and treat congestive heart failure?

Most people take about 100 mg of CoQ10 daily. But if you have heart failure or if you’re at high risk for it, then you may be taking as much as 200 mg per day. However, new research suggests this might not be enough.

To determine the best daily dose, you have to look at how the dose impacts your heart’s ejection fraction. That’s the percentage of volume pumped out per beat. A normal heart has an ejection fraction of about 60+%. With heart failure, that amount falls to below 30%. When you get below 25%, your life hangs in the balance. Any improvement, no matter how small, can have a major impact on your health.

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So a group of researchers did a review of 11 CoQ10 studies. They confirmed that the nutrient produces a 3.7% improvement in ejection fraction and a 0.28 Liter/minute increase in heart output. For those patients not taking ACE inhibitor drugs, the improvement was even better. Their ejection fraction improvement was 6.74% (nearly double).

Here’s where this gets interesting. The dosage in the studies ranged from 60 mg per day to 200 mg per day. Sounds reasonable. But most alternative doctors will tell you this isn’t nearly enough. Most alternative docs are now using at least 300 mg daily. And many will use as much as 600 mg per day for congestive heart failure.

So if you have heart failure, or if you’re at high risk for it, be sure you’re taking enough. Unfortunately, CoQ10 is relatively expensive at these doses. So I recommend taking a form of CoQ10 that’s better absorbed. This is Ubiquinol CoQ10. With this form, you need to take only half the dose (150-300 mg).

If you’re not sure if you’re taking enough, have your doctor check your blood level of CoQ10. You should be way over the top of the lab reference range. This is one place where more is better.

Your insider for better health,

“The impact of coenzyme Q10 on systolic function in patients with chronic heart failure,” Sander S, Coleman SI, et al, Journal of Cardiac Failure, 2006; 12(6): 464-72. (Address: University of Connecticut School of Pharmacy, Storrs, Connecticut 06269, USA).

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